Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022777 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL3036858 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL1920807 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL95619 | 1.00 | — | — | |
| SCHEMBL3027678 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL1920210 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL3034311 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL26096 | 1.00 | — | — | |
| SCHEMBL329468 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL1218164 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1097 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655225-B2 | Antimycobacterial heterocyclic amides | CRESTONE, INC. (US) | 2023-05-23 | — | — | US | claimed |
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | claimed |
| US-20210002239-A1 | Novel Antimycobacterial Heterocyclic Amides | CRESTONE, INC. | 2021-01-07 | — | — | US | claimed |
| EP-3758697-A1 | NOVEL ANTIMYCOBACTERIAL HETEROCYCLIC AMIDES | Crestone, Inc. (US) | 2021-01-06 | — | — | EP | claimed |
| US-9063411-B2 | Additive for resist and resist composition comprising same | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2015-06-23 | — | — | US | claimed |
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2014-06-12 | — | — | US | claimed |
| US-8680234-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2014-03-25 | — | — | US | claimed |
| US-20130171561-A1 | ADDITIVE FOR RESIST AND RESIST COMPOSITION COMPRISING SAME | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2013-07-04 | — | — | US | claimed |
| US-20130171560-A1 | ADDITIVE FOR RESIST AND RESIST COMPOSITION COMPRISING SAME | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2013-07-04 | — | — | US | claimed |
| US-8329645-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-12-11 | — | — | US | claimed |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2010-11-18 | — | — | US | claimed |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-08-27 | — | — | US | claimed |
| US-20240216389-A1 | DRUG FOR PREVENTING AND/OR TREATING POLYCYSTIC KIDNEY DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-07-04 | — | — | US | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |
| US-11957691-B2 | Drug for preventing and/or treating polycystic kidney disease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-04-16 | — | — | US | disclosed |
| EP-4349872-A1 | ß GLUCAN ESTER DERIVATIVE | LIXIL Corporation (JP) | 2024-04-10 | — | — | EP | disclosed |
| US-4054651-A | Method of contraception | RICHARDSON-MERRELL INC. (US) | 1977-10-18 | — | — | US | disclosed |
| US-4013762-A | STEROIDS WITHOUT ANDROGENIZING EFFECT | RICHARDSON-MERRELL INC. (US) | 1977-03-22 | — | — | US | disclosed |
| US-4006122-A | STORAGE STABLE | THE UPJOHN COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | ALDH1A1 4876/4885CES2 4709/4885CES1 3391/4885 |
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | SLC11A2, TLR2, TLR5 | ALDH1A1 4808/4885CES2 4455/4885CES1 3527/4885 |
| US-11655225-B2 | Antimycobacterial heterocyclic amides | AADAC, CPS1, NAT1 | ALDH1A1 1850/4885CES2 730/4885CES1 950/4885 |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | ALDH1A1 4876/4885CES2 4709/4885CES1 3391/4885 |
| US-11957691-B2 | Drug for preventing and/or treating polycystic kidney disease | PKD1, PKD2, SSTR5 | ALDH1A1 3354/4885CES2 3350/4885CES1 1326/4885 |
| US-20210002239-A1 | Novel Antimycobacterial Heterocyclic Amides | AADAC, CPS1, ACAT1 | ALDH1A1 2417/4885CES2 810/4885CES1 1028/4885 |
| US-20240216389-A1 | DRUG FOR PREVENTING AND/OR TREATING POLYCYSTIC KIDNEY DISEASE | PKD1, PKD2, SSTR5 | ALDH1A1 3354/4885CES2 3350/4885CES1 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.