Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022777 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL3036858 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL59917 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL95619 | 1.00 | — | — | |
| SCHEMBL3027678 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL1920210 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL3034311 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL26096 | 1.00 | — | — | |
| SCHEMBL329468 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A | |
| SCHEMBL1218164 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CES2CES1EPHX1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2014-06-12 | — | — | US | claimed |
| US-8680234-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2014-03-25 | — | — | US | claimed |
| US-8329645-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-12-11 | — | — | US | claimed |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2010-11-18 | — | — | US | claimed |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-08-27 | — | — | US | claimed |
| EP-2478981-B1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2020-06-18 | — | — | US | disclosed |
| US-10478385-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2019-11-19 | — | — | US | disclosed |
| US-20190000722-A1 | DENTAL ADHESIVE MATERIAL KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2019-01-03 | — | — | US | disclosed |
| WO-2018195078-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-10-25 | — | — | WO | disclosed |
| EP-3391871-A1 | DENTAL ADHESIVE MATERIAL KIT | Kuraray Noritake Dental Inc. (JP) | 2018-10-24 | — | — | EP | disclosed |
| US-9704612-B2 | Composition of silver-conjugated compound composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-07-11 | — | — | US | disclosed |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | BAYER CROPSCIENCE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| EP-0914307-B1 | ENZYMATICALLY REMOVABLE LINKERS FOR SOLID PHASE SYNTHESIS | BASF AG (DE) | 2004-09-15 | — | — | EP | disclosed |
| US-6271345-B1 | FOR SYNTHESIS OF ORGANIC COMPOUNDS, COMBINATORIAL CHEMISTRY | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0914307-A1 | ENZYMATICALLY REMOVABLE LINKERS FOR SOLID PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998001406-A1 | ENZYMATICALLY REMOVABLE LINKERS FOR SOLID PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |
| US-5658926-A | ANTICOAGULANTS, ANTIHISTAMINES, ANTIARRHYTHMIC, CARTIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | QSOX1, CYC1, CBR3 | ALDH1A1 1058/4885CES2 458/4885CES1 333/4885 |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | ALDH1A1 4876/4885CES2 4709/4885CES1 3391/4885 |
| US-10478385-B2 | Dental adhesive material kit | VCL, MVD, MAT2B | ALDH1A1 180/4885CES2 3510/4885CES1 4716/4885 |
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | SLC11A2, TLR2, TLR5 | ALDH1A1 4808/4885CES2 4455/4885CES1 3527/4885 |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | DDOST, MGAM, MSN | ALDH1A1 4571/4885CES2 3268/4885CES1 3912/4885 |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | ALDH1A1 4876/4885CES2 4709/4885CES1 3391/4885 |
| US-20190000722-A1 | DENTAL ADHESIVE MATERIAL KIT | VCL, MVD, MAT2B | ALDH1A1 180/4885CES2 3510/4885CES1 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.