Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.54 |
| ▸ | STS | P08842 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992874 | 0.88 | KDM1A (0.56) | CYP19A1STSKDM4EKDM1AKCNH2 | |
| SCHEMBL5991163 | 0.81 | MAOA (0.54) | CYP19A1STSAOC3CACNA1GCACNA1B | |
| SCHEMBL5436760 | 0.81 | MAOA (0.54) | CYP19A1STSAOC3CACNA1GCACNA1B | |
| SCHEMBL5992333 | 0.79 | LOXL2 (0.54) | CYP19A1STSCA2KCNH2MEN1 | |
| SCHEMBL5991160 | 0.75 | CYP2A6 (0.55) | CYP19A1KDM1AALDH1A1 | |
| SCHEMBL5992091 | 0.75 | CYP19A1 (0.62) | CYP19A1STS | |
| SCHEMBL5993010 | 0.75 | CYP19A1 (0.48) | CYP19A1STSKDM1AKCNH2 | |
| SCHEMBL14549047 | 0.73 | CYP19A1 (0.56) | CYP19A1STS | |
| SCHEMBL14548899 | 0.73 | CYP19A1 (0.70) | CYP19A1STS | |
| SCHEMBL3436222 | 0.73 | AOC3 (0.69) | CYP19A1AOC3CA2KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572665-B1 | 1-N-PHENYLAMINO-1H-IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS | THERAMEX (MC) | 2006-05-03 | — | — | EP | disclosed |
| EP-1572665-A2 | 1-N-PHENYLAMINO-1H-IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS | LABORATOIRE THERAMEX (MC) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054983-A2 | 1-N-PHENYLAMINO-1H-IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS | LABORATOIRE THERAMEX (MC) | 2004-07-01 | — | — | WO | disclosed |
| EP-1431292-A1 | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors | LABORATOIRE THERAMEX (MC) | 2004-06-23 | — | — | EP | disclosed |
| US-6737433-B1 | ESTROGEN DEPENDENT ANTITUMOR AGENTS | LABORATOIRE THERAMEX (MC) | 2004-05-18 | — | — | US | disclosed |