Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256851 | 0.83 | KMT2A (0.58) | KMT2AMEN1GPR84NPC1NR4A2 | |
| SCHEMBL13753409 | 0.77 | NR4A2 (0.64) | KMT2AMEN1GPR84NPC1NR4A2 | |
| SCHEMBL29113776 | 0.76 | ALDH1A1 (0.56) | KMT2AGPR84NPC1NR4A2CREBBP | |
| SCHEMBL1586378 | 0.76 | ALDH1A1 (0.56) | KMT2AGPR84NPC1NR4A2CREBBP | |
| SCHEMBL13753458 | 0.74 | ALDH1A1 (0.57) | KMT2AMEN1GPR84NPC1NR4A2 | |
| SCHEMBL9387748 | 0.74 | POLB (0.54) | KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL29511928 | 0.74 | KMT2A (0.54) | KMT2AMEN1GPR84NPC1NR4A2 | |
| Hydrochloric Acid SCHEMBL29435427 | 0.74 | GPR84 (0.74) | KMT2AMEN1GPR84NPC1NR4A2 | |
| SCHEMBL27837528 | 0.74 | GPR84 (0.74) | KMT2AMEN1GPR84NPC1NR4A2 | |
| Hydrochloric Acid SCHEMBL7437913 | 0.74 | GPR84 (0.74) | KMT2AMEN1GPR84NPC1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917462-B1 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060030553-A1 | Cell adhesion inhibitors | ZHENG ZHONGLI | 2006-02-09 | — | — | US | disclosed |
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040053907-A1 | Cell adhesion inhibitors | BIOGEN, INC. A MASSACHUSETTS CORPORATION. | 2004-03-18 | — | — | US | disclosed |
| US-6686350-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2004-02-03 | — | — | US | disclosed |
| EP-0917462-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004247-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053907-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | KMT2A 3376/4885MEN1 1437/4885GPR84 1870/4885 |
| US-20060030553-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | KMT2A 3376/4885MEN1 1437/4885GPR84 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.