Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641295 | 0.82 | AKR1B1 (0.51) | AKR1C3AKR1C2ALOX5PPARGPPARA | |
| SCHEMBL8120419 | 0.82 | AKR1B1 (0.51) | AKR1C3AKR1C2ALOX5PPARGPPARA | |
| SCHEMBL448107 | 0.82 | AKR1B1 (0.51) | AKR1C3AKR1C2ALOX5PPARGPPARA | |
| SCHEMBL27890998 | 0.80 | AKR1B1 (0.50) | AKR1C3AKR1C2ALOX5PPARGPPARA | |
| SCHEMBL28690577 | 0.80 | AKR1C3 (0.59) | AKR1C3AKR1C2ALOX5PPARGPPARA | |
| SCHEMBL599428 | 0.78 | AKR1C3 (0.55) | AKR1C3AKR1C2PPARGPPARAGPR84 | |
| SCHEMBL9420888 | 0.77 | CXCL8 (0.46) | AKR1C3AKR1C2PTGS2CXCL8KDM4E | |
| SCHEMBL599732 | 0.76 | AKR1B1 (0.47) | AKR1C3AKR1C2ALOX5PPARGPPARA | |
| SCHEMBL11766705 | 0.74 | PPARG (0.49) | AKR1C3AKR1C2PPARGPPARAPTGS2 | |
| SCHEMBL28948611 | 0.74 | ALOX5 (0.52) | AKR1C3AKR1C2ALOX5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |