Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 11/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273173 | 0.78 | CHRM4 (0.57) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5730415 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL30410968 | 0.72 | CDC7 (0.51) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL14784887 | 0.70 | CHRM4 (0.56) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL432011 | 0.68 | KDM4E (0.67) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL2300776 | 0.67 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL18666379 | 0.66 | HPGD (0.53) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL278791 | 0.66 | POLB (0.65) | KDM4EALDH1A1POLBKMT2AGAA | |
| SCHEMBL30989229 | 0.66 | KDM4E (0.66) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL14794166 | 0.65 | CHRM4 (0.60) | KDM4EALDH1A1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060014144-A1 | Pseudonucleotide comprising an intercalator | HUMAN GENETIC SIGNATURES PROPRIETARY LTD. (AU) | 2006-01-19 | — | — | US | disclosed |
| WO-2003052133-A2 | OLIGONUCLEOTIDE ANALOGUES COMPRISING INTERCALATOR PSEUDONUCLEOTIDES | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014144-A1 | Pseudonucleotide comprising an intercalator | POLN, POLRMT, SUB1 | KDM4E 3483/4885ALDH1A1 1636/4885HPGD 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.