Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 11/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 11/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994241 | 1.00 | KCNE1 (0.36) | KCNE1KCNQ1ABCC9STSKCNH2 | |
| SCHEMBL5988198 | 0.88 | ABCC9 (0.35) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL5988200 | 0.88 | ABCC9 (0.35) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL2891954 | 0.81 | ALDH1A1 (0.39) | KCNE1KCNQ1ABCC9STSNR3C1 | |
| SCHEMBL5988553 | 0.81 | ALDH1A1 (0.39) | KCNE1KCNQ1ABCC9STSNR3C1 | |
| SCHEMBL2891256 | 0.80 | ALDH1A1 (0.42) | KCNE1KCNQ1 | |
| SCHEMBL2880113 | 0.80 | ABCC9 (0.39) | ABCC9STS | |
| SCHEMBL2880116 | 0.80 | ABCC9 (0.39) | ABCC9STS | |
| SCHEMBL5988536 | 0.78 | ABCC9 (0.35) | ABCC9KCNH2 | |
| SCHEMBL5988534 | 0.78 | ABCC9 (0.35) | ABCC9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-1718629-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR THE TREATMENT OF ARRHYTMIA | Nissan Chemical Industries, Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080368-A2 | BENZOPYRAN COMPOUND USEFUL FOR THE TREATMENT OF ARRHYTMIA | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-01 | — | — | WO | disclosed |