Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599245 | 0.78 | PPARG (0.52) | SLC22A12PPARGPPARAHDAC4HDAC2 | |
| SCHEMBL6927908 | 0.77 | PTPN1 (0.46) | SLC6A2SLC6A4SLC6A3HDAC4HDAC2 | |
| SCHEMBL25402506 | 0.71 | HDAC4 (0.51) | SLC6A2SLC6A4SLC6A3SLC22A12PPARG | |
| SCHEMBL17852132 | 0.71 | HDAC4 (0.43) | SLC6A2SLC6A4SLC6A3SLC22A12HDAC4 | |
| SCHEMBL73063 | 0.70 | HDAC3 (0.61) | HDAC4HDAC2HDAC8CYP2C19CYP1A2 | |
| SCHEMBL84188 | 0.68 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3HDAC4HDAC2 | |
| SCHEMBL29618929 | 0.68 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3HDAC4HDAC2 | |
| SCHEMBL30610922 | 0.68 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3HDAC4HDAC2 | |
| Bromomethane SCHEMBL209562 | 0.68 | HDAC3 (0.59) | HDAC4HDAC2HDAC8CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL3674757 | 0.68 | HDAC3 (0.59) | HDAC4HDAC2HDAC8CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |