Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994364 | 1.00 | CYP3A4 (0.51) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL14619857 | 1.00 | CYP3A4 (0.51) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL8870031 | 0.85 | ANPEP (0.46) | CYP3A4ALDH1A1TSHRHSD17B10PKM | |
| SCHEMBL27776733 | 0.84 | CYP2D6 (0.43) | CYP2C19PKMSMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL9230354 | 0.82 | CYP3A4 (0.55) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL2879779 | 0.82 | CYP3A4 (0.59) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL6578433 | 0.82 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| Hydrochloric Acid SCHEMBL29096620 | 0.82 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL9274935 | 0.82 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL6578431 | 0.82 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987263-B2 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-03-24 | — | — | US | disclosed |
| CN-100582085-C | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RES & DEV | 2010-01-20 | — | — | CN | disclosed |
| US-20060173053-A1 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-08-03 | — | — | US | disclosed |
| CN-1703394-A | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RES & DEV (IL) | 2005-11-30 | — | — | CN | disclosed |
| EP-1551495-A2 | BASIC ESTERS OF FATTY ALCOHOLS AND THEIR USE AS ANTI-INFLAMMATORY OR IMMUNOMODULATORY AGENTS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004032824-A2 | BASIC ESTERS OF FATTY ALCOHOLS AND THEIR USE AS ANTI-INFLAMMATORY OR IMMUNOMODULATORY AGENTS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173053-A1 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | ALOX12, ALOX15, ALOX15B | CYP3A4 607/4885ALDH1A1 447/4885TSHR 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.