SCHEMBL5994916

SCHEMBL5994916

CCC(C)P(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
GAA P10253 3/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
TP53 P04637 1/20 0.35
RAB9A P51151 2/20 0.34
TSHR P16473 1/20 0.34
TYK2 P29597 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PYGL P06737 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
UTS2R Q9UKP6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5996504 0.91 TYK2 (0.42) GAAMAPTTAS1R3TAS1R1TAS1R2
SCHEMBL5995811 0.89 KMT2A (0.39) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL5998075 0.89 GAA (0.38) KMT2AMEN1GAAPOLBLMNA
SCHEMBL5996111 0.88 TSHR (0.35) KMT2AMEN1POLBHPGDLMNA
SCHEMBL6467319 0.87 KMT2A (0.41) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL5995231 0.85 KMT2A (0.37) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL5997379 0.84 UTS2R (0.35) KMT2AMEN1LMNASMN1; SMN2MAPT
SCHEMBL5996660 0.82 TAS1R3 (0.41) KMT2AMEN1LMNASMN1; SMN2MAPT
SCHEMBL6466911 0.81 L3MBTL1 (0.38) KMT2AMEN1LMNASMN1; SMN2TAS1R3
SCHEMBL5995376 0.81 LMNA (0.39) KMT2AMEN1POLBHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 KMT2A 1784/4885MEN1 3862/4885GAA 4801/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 KMT2A 761/4885MEN1 2456/4885GAA 4108/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 KMT2A 1577/4885MEN1 3695/4885GAA 4741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.