Amotosalen

Amotosalen

SCHEMBL599618

Cc1oc2c(C)c3oc(=O)cc(C)c3cc2c1COCCN

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
KDM4E B2RXH2 8/20 0.44
ALDH1A1 P00352 6/20 0.44
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
HTR2C P28335 1/20 0.44
ADORA2A P29274 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.42
HSD17B10 Q99714 4/20 0.40
HPGD P15428 4/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 3/20 0.39
MCL1 Q07820 2/20 0.39
UBE2N P61088 1/20 0.39
LMNA P02545 5/20 0.38
HTT P42858 3/20 0.38
GAA P10253 2/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amotosalen SCHEMBL29442584 1.00 MAOA (0.44) MAOAMAOBKDM4EALDH1A1MAPK1
Amotosalen SCHEMBL4197287 0.99 MAOA (0.43) MAOAMAOBKDM4EALDH1A1MAPK1
Amotosalen SCHEMBL15229366 0.98 MAOA (0.42) MAOAMAOBKDM4EALDH1A1MAPK1
SCHEMBL3359066 0.93 MAOA (0.42) MAOAMAOBKDM4EALDH1A1MAPK1
SCHEMBL6993313 0.88 MCL1 (0.41) MAOAMAOBKDM4EALDH1A1MAPK1
SCHEMBL1115728 0.88 L3MBTL1 (0.44) MAOAMAOBKDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL7001517 0.86 MCL1 (0.41) MAOAMAOBKDM4EALDH1A1MAPK1
SCHEMBL13078690 0.86 MAOA (0.50) MAOAMAOBKDM4EALDH1A1MAPK1
SCHEMBL21585417 0.85 MAOA (0.42) MAOAMAOBKDM4EALDH1A1MAPK1
SCHEMBL21585418 0.85 MAOB (0.42) MAOAMAOBKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558463-B2 Portable centrifuge device and method of use ABC Med Tech Corp. (US) 2026-02-24 US claimed
US-12514876-B2 Cryoprecipitate compositions and methods of preparation thereof CERUS CORPORATION (US) 2026-01-06 US claimed
US-20250375477-A1 SELECTIVE TOLERIZATION - METHODS OF SELECTIVELY GENERATING TOLEROGENIC DENDRITIC CELLS TRANSIMMUNE AG (DE) 2025-12-11 US claimed
US-20250345471-A1 SYSTEMS AND METHODS FOR TREATING BIOLOGICAL FLUIDS CERUS CORP (US) 2025-11-13 US claimed
EP-4606379-A2 KITS AND METHODS FOR PREPARING PATHOGEN-INACTIVATED PLATELET COMPOSITIONS Cerus Corporation (US) 2025-08-27 EP claimed
US-20250084370-A1 METHODS FOR SELECTIVELY REDUCING IMMUNOGENICITY IN A TRANSPLANT TRANSIMMUNE AG (DE) 2025-03-13 US claimed
US-12214092-B2 Systems and methods for treating biological fluids CERUS CORPORATION (US) 2025-02-04 US claimed
US-20240271094-A1 COMPOSITIONS AND METHODS FOR PATHOGEN INACTIVATION OF PLATELETS CERUS CORPORATION 2024-08-15 US claimed
EP-4410318-A2 CRYOPRECIPITATE COMPOSITIONS AND METHODS OF PREPARATION THEREOF Cerus Corporation (US) 2024-08-07 EP claimed
EP-4376860-A1 METHODS FOR SELECTIVELY REDUCING IMMUNOGENICITY IN A TRANSPLANT Transimmune AG (DE) 2024-06-05 EP claimed
WO-1998030327-A1 METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS CERUS CORPORATION (US) 1998-07-16 WO claimed
EP-0840781-A1 METHODS AND DEVICES FOR THE REMOVAL OF PSORALENS FROM BLOOD PRODUCTS Cerus Corporation (US) 1998-05-13 EP claimed
WO-1997021346-A1 INACTIVATION OF NON-ENVELOPED VIRUS CERUS CORPORATION (US) 1997-06-19 WO claimed
US-5593823-A FOR A SUFFICIENT DURATION, INTENSITY AND WAVELENGTH CERUS CORPORATION (US) 1997-01-14 US claimed
WO-1996040857-A1 METHODS AND DEVICES FOR THE REMOVAL OF PSORALENS FROM BLOOD PRODUCTS CERUS CORPORATION (US) 1996-12-19 WO claimed
WO-1996039820-A1 METHODS OF INACTIVATING LEUKOCYTES AND INHIBITING CYTOKINE PRODUCTION IN BLOOD PRODUCTS CERUS CORPORATION (US) 1996-12-19 WO claimed
WO-1996014739-A1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD CERUS CORPORATION (US) 1996-05-23 WO claimed
EP-0707476-A1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD STERITECH, INC (US) 1996-04-24 EP claimed
US-5399719-A 4'-/4-Amino-2-oxa/butyl-4,5',8-trimethylpsoralen; preparation of 4'-/omega-amino-2-oxa/alkyl-4,5',8-trimethylpsoralens by reacting analogous omega-hydroxy compound with methanesulfonyl chloride and base, with sodium azide, with reducing agent STERITECH, INC. (US) 1995-03-21 US claimed
WO-1995000141-A1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD STERITECH, INC. (US) 1995-01-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558463-B2 Portable centrifuge device and method of use SELL, CEP170, CFD MAOA 4721/4885MAOB 4791/4885KDM4E 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.