SCHEMBL599730

SCHEMBL599730

C[C@@H](C(=O)OC(c1cccc2ccccc12)c1cccc2ccccc12)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
SLC6A4 P31645 1/20 0.41
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
CASP1 P29466 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
AKR1B1 P15121 1/20 0.40
PTGER4 P35408 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598815 0.90 RAB9A (0.39) ALDH1A1AKR1B1AKR1C3AKR1C2LMNA
SCHEMBL17681440 0.89 MEN1 (0.46) ALDH1A1CASP1CYP2C9CYP2C19PTGER4
SCHEMBL600002 0.89 UTS2R (0.44) ALDH1A1SLC6A4PTGS2CYP2C19
SCHEMBL30532624 0.88 ALDH1A1 (0.47) ALDH1A1SLC6A4CASP1CYP2C9HPGD
SCHEMBL17681406 0.88 ALDH1A1 (0.39) ALDH1A1SLC6A4PTGS1PTGS2HPGD
SCHEMBL606226 0.88 TDP1 (0.48) ALDH1A1PTGS2GAA
SCHEMBL17681452 0.87 ALDH1A1 (0.39) ALDH1A1PTGS1PTGS2HPGDHTT
SCHEMBL17681428 0.87 AKR1C3 (0.43) ALDH1A1PTGS1PTGS2AKR1B1AKR1C3
SCHEMBL17681403 0.86 TDP1 (0.49) PTGS1PTGS2AKR1B1AKR1C3AKR1C2
SCHEMBL17681419 0.86 L3MBTL1 (0.49) SLC6A4PTGS1PTGS2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315442-B2 Method for manufacturing optically active carboxylic acid ester TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2016-04-19 US disclosed
US-8115008-B2 Method for producing optically active ester and method for producing optically active carboxylic acid TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2012-02-14 US disclosed