Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591131 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL31268114 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL27960948 | 0.74 | MEN1 (0.59) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL31268138 | 0.73 | MEN1 (0.55) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL3916363 | 0.72 | ADRA2A (0.40) | LMNATDP1ALDH1A1 | |
| SCHEMBL820361 | 0.71 | IDO1 (0.61) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL646254 | 0.70 | GPR84 (0.55) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL21803776 | 0.70 | IDO1 (0.65) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL14272982 | 0.70 | IDO1 (0.45) | MEN1KMT2ALMNAIDO1MAPT | |
| SCHEMBL5936671 | 0.69 | GAA (0.62) | MEN1KMT2ALMNAIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |