SCHEMBL646254

SCHEMBL646254

Cn1cc(O)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.55
ALDH1A1 P00352 4/20 0.52
IMPDH2 P12268 2/20 0.52
NR4A2 P43354 1/20 0.50
IDO1 P14902 1/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
CCNT1 O60563 1/20 0.49
CDK9 P50750 1/20 0.49
MITF O75030 1/20 0.49
HTT P42858 1/20 0.49
HTR2A P28223 1/20 0.48
MEN1 O00255 1/20 0.47
GPR3 P46089 1/20 0.46
KDM4E B2RXH2 2/20 0.46
CCNE2 O96020 1/20 0.46
CDK4 P11802 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6338665 0.90 ALDH1A1 (0.49) GPR84ALDH1A1IMPDH2NR4A2IDO1
Acetic Acid SCHEMBL2543982 0.90 POLB (0.56) GPR84ALDH1A1IMPDH2NR4A2POLB
SCHEMBL2747859 0.84 HTT (0.53) GPR84ALDH1A1IMPDH2NR4A2POLB
SCHEMBL29084923 0.77 GPR3 (0.41) GPR84ALDH1A1IMPDH2NR4A2IDO1
Octanoic Acid SCHEMBL1122164 0.77 OXER1 (0.53) CCNT1CDK9KDM4ECDK2
SCHEMBL27535494 0.77 KDM4E (0.39) GPR84ALDH1A1IMPDH2NR4A2IDO1
SCHEMBL146530 0.74 GPR84 (0.57) GPR84ALDH1A1IMPDH2NR4A2IDO1
SCHEMBL21035552 0.74 GPR84 (0.57) GPR84ALDH1A1IMPDH2NR4A2IDO1
SCHEMBL29473770 0.74 GPR84 (0.57) GPR84ALDH1A1IMPDH2NR4A2IDO1
SCHEMBL10395712 0.74 GPR84 (0.57) GPR84ALDH1A1IMPDH2NR4A2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11605790-B2 Monosubstituted diazabenzimidazole carbene metal complexes for use in organic light emitting diodes UDC IRELAND LIMITED (IE) 2023-03-14 US claimed
US-10590460-B2 Selective enrichment medium for carbapenem-resistant bacteria RAMBACH ALAIN (FR) 2020-03-17 US claimed
US-20180163247-A1 SELECTIVE ENRICHMENT MEDIUM FOR CARBAPENEM-RESISTANT BACTERIA RAMBACH ALAIN (FR) 2018-06-14 US claimed
US-20160177368-A1 SELECTIVE ENRICHMENT MEDIUM FOR CARBAPENEM-RESISTANT BACTERIA RAMBACH ALAIN (FR) 2016-06-23 US claimed
US-9303282-B2 Selective enrichment medium for carbapenem-resistant bacteria RAMBACH ALAIN (FR) 2016-04-05 US claimed
EP-2718458-B1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2015-07-08 EP claimed
EP-2084293-B1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2014-08-13 EP claimed
US-20140212905-A1 Novel Method for Detection of Beta-D-Glucuronidase BIOSYNTH AG (CH) 2014-07-31 US claimed
WO-2014116727-A1 ONE-STEP RAPID ASSAY FOR THE DETECTION OF INHIBITORS OF ENZYMES ANP TECHNOLOGIES, INC. (US) 2014-07-31 WO claimed
EP-2718458-A1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE Biosynth AG (CH) 2014-04-16 EP claimed
WO-2002101082-A2 CULTURE MEDIUM FOR DETECTING AND/OR DISCRIMINATING ENTEROCOCCUS AND METHOD THEREFOR RAMBACH ALAIN (FR) 2002-12-19 WO claimed
WO-2002053705-A1 CULTURE MEDIUM FOR DETECTING BACTERIA OF LISTERIA GENUS RAMBACH ALAIN (FR) 2002-07-11 WO claimed
WO-2002000922-A1 VIBRIO BACTERIA DETECTION AND/OR DIFFERENTIATION RAMBACH ALAIN (FR) 2002-01-03 WO claimed
US-6165743-A Culture medium for revealing enterohemorrhagic E. coli bacteria and procedure therefor RAMBACH ALAIN (FR) 2000-12-26 US claimed
EP-0553741-B1 Fluorogenic and chromogenic betalactamase substrates BECTON DICKINSON CO (US) 2000-08-23 EP claimed
US-5962251-A INTRODUCING AT LEAST TWO CHROMOGENS WHICH ARE ENZYME SUBSTRATES FOR A MICROORGANISM STRAIN INTO CULTURE MEDIUM, IDENTIFYING ACCESSORY COLOR PRODUCED BY ENZYMATIC ACTIVITY RAMBACH ALAIN (FR) 1999-10-05 US claimed
EP-0711360-B1 Process for the identification of microorganisms using at least two chromogens RAMBACH ALAIN (FR) 1998-03-11 EP claimed
US-5716799-A QUALITATIVE COLORIMETRIC ANALYSIS RAMBACH ALAIN (FR) 1998-02-10 US claimed
EP-0711359-B1 MICROORGANISM IDENTIFICATION METHOD USING A MEDIUM CONTAINING ADDED CARBOHYDRATE RAMBACH ALAIN (FR) 1997-05-28 EP claimed
EP-0237394-A1 Diagnostic agent and its preparation process for detecting urogenital infections ARLEY-GUILLAUBEY LABORATOIRES (FR) 1987-09-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11605790-B2 Monosubstituted diazabenzimidazole carbene metal complexes for use in organic light emitting diodes DDT, OCIAD1, OCIAD2 GPR84 1171/4885ALDH1A1 563/4885IMPDH2 2611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.