SCHEMBL5997236

SCHEMBL5997236

[CH2]c1ccc2cc(O)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.58
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
HIF1A Q16665 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CYP1A2 P05177 2/20 0.56
ESR2 Q92731 12/20 0.52
ESR1 P03372 11/20 0.52
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
HSD17B1 P14061 1/20 0.46
CYP2B6 P20813 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B2 P37059 1/20 0.46
F12 P00748 1/20 0.45
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364786 0.83 CYP1A2 (0.77) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL627219 0.83 CYP1A2 (0.77) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL69484 0.83 CYP1A2 (0.77) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL1178667 0.83 CYP2A6 (0.37) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL27845395 0.80 CYP1A2 (0.72) CYP3A4ALOX15TSHRHIF1AHSD17B10
Hydroquinone SCHEMBL6689552 0.80 ESR2 (0.74) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL6185635 0.79 LCK (0.45) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL29973107 0.77 CYP1A2 (0.68) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL29405718 0.77 CYP1A2 (0.68) CYP3A4ALOX15TSHRHIF1AHSD17B10
SCHEMBL392290 0.77 CYP1A2 (0.68) CYP3A4ALOX15TSHRHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
CN-108484449-A Composition, method and system for synthesizing and using developer 蓝瑟斯医学影像公司 2018-09-04 CN disclosed
CN-104159890-B Compositions, methods, and systems for synthesis and use of imaging agents 蓝瑟斯医学影像公司 2018-04-10 CN disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 EP disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
EP-2455812-A2 Photosensitive copolymer and photoresist composition Rohm and Haas Electronic Materials LLC (US) 2012-05-23 EP disclosed
US-7087759-B2 for controlling weight; pyrrolidine or piperidine compounds THE PROCTER & GAMBLE COMPANY (US) 2006-08-08 US disclosed
US-20060106059-A1 Melanocortin receptor ligands MAZUR WIESLAW A 2006-05-18 US disclosed
EP-1390361-A4 MELANOCORTIN RECEPTOR LIGANDS PROCTER & GAMBLE (US) 2005-10-05 EP disclosed
US-6911447-B2 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY (US) 2005-06-28 US disclosed
US-20040224985-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2004-11-11 US disclosed
CN-1543461-A Melanocortin receptor ligands 2004-11-03 CN disclosed
EP-1390361-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2004-02-25 EP disclosed
US-20030109556-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2003-06-12 US disclosed
WO-2002085925-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109556-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R CYP3A4 850/4885ALOX15 2264/4885TSHR 65/4885
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 CYP3A4 1085/4885ALOX15 2577/4885TSHR 507/4885
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 CYP3A4 2896/4885ALOX15 858/4885TSHR 2151/4885
US-20060106059-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R CYP3A4 1057/4885ALOX15 1585/4885TSHR 65/4885
US-20040224985-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R CYP3A4 850/4885ALOX15 2264/4885TSHR 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.