Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | F7 | P08709 | 3/20 | 0.34 |
| ▸ | F3 | P13726 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623306 | 1.00 | GGT1 (0.41) | GGT1ARG1ARG2ALDH1A1CYP19A1 | |
| SCHEMBL5839964 | 0.83 | GGT1 (0.41) | GGT1ARG1ARG2ALDH1A1MAPT | |
| SCHEMBL5839956 | 0.83 | GGT1 (0.41) | GGT1ARG1ARG2ALDH1A1MAPT | |
| SCHEMBL6380325 | 0.79 | GGT1 (0.42) | GGT1ARG1ARG2ALDH1A1MAPT | |
| SCHEMBL5839453 | 0.79 | GGT1 (0.42) | GGT1ARG1ARG2ALDH1A1MAPT | |
| SCHEMBL6380315 | 0.79 | GGT1 (0.42) | GGT1ARG1ARG2ALDH1A1MAPT | |
| SCHEMBL5839448 | 0.79 | GGT1 (0.42) | GGT1ARG1ARG2ALDH1A1MAPT | |
| SCHEMBL622530 | 0.79 | PPARG (0.50) | ALDH1A1CYP19A1MAPTPPARGFFAR1 | |
| SCHEMBL600895 | 0.79 | PPARG (0.50) | ALDH1A1CYP19A1MAPTPPARGFFAR1 | |
| SCHEMBL2481158 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774114-B2 | Respiratory syncytial virus (RSV) replication inhibitors | FONDATION THE ARK (CH) | 2020-09-15 | — | — | US | disclosed |
| US-20170152292-A1 | RESPIRATORY SYNCYTIAL VIRUS (RSV) REPLICATION INHIBITORS | INSTITUT NATIONAL DE RECHERCHE AGRONOMIQUE (INRA) (FR) | 2017-06-01 | — | — | US | disclosed |
| US-9175047-B2 | Peptidomimetic macrocycles | AILERON THERAPEUTICS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-8324153-B2 | Antiviral cell-penetrating peptides | NEW YORK BLOOD CENTER, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120101047-A1 | PEPTIDOMIMETIC MACROCYCLES | Aileron Therapetics Inc. (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120040889-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101047-A1 | PEPTIDOMIMETIC MACROCYCLES | GLP1R, PROKR1, VIP | GGT1 2156/4885ARG1 204/4885ARG2 121/4885 |
| US-20120040889-A1 | PEPTIDOMIMETIC MACROCYCLES | ZC3HAV1, HAVCR2, ZC3HAV1L | GGT1 3065/4885ARG1 355/4885ARG2 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.