Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622530 | 1.00 | PPARG (0.50) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL11431507 | 0.84 | ACLY (0.58) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL8108031 | 0.84 | ACLY (0.58) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL3275097 | 0.81 | ACLY (0.58) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1114649 | 0.80 | ACLY (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1114645 | 0.80 | ACLY (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL5839448 | 0.79 | GGT1 (0.42) | MAPTBLMHSD17B10KMT2ACYP1A2 | |
| SCHEMBL6380325 | 0.79 | GGT1 (0.42) | MAPTBLMHSD17B10KMT2ACYP1A2 | |
| SCHEMBL5839453 | 0.79 | GGT1 (0.42) | MAPTBLMHSD17B10KMT2ACYP1A2 | |
| SCHEMBL6380315 | 0.79 | GGT1 (0.42) | MAPTBLMHSD17B10KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175047-B2 | Peptidomimetic macrocycles | AILERON THERAPEUTICS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-8324153-B2 | Antiviral cell-penetrating peptides | NEW YORK BLOOD CENTER, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120040889-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040889-A1 | PEPTIDOMIMETIC MACROCYCLES | ZC3HAV1, HAVCR2, ZC3HAV1L | PPARG 3619/4885PPARD 3257/4885PPARA 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.