SCHEMBL5997579

SCHEMBL5997579

CC(C)(C)c1cc(C(C)(C)C)c(C(=O)CCP)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.36
NR5A1 Q13285 1/20 0.36
GLRA3 O75311 1/20 0.35
GLRB P48167 1/20 0.35
ELANE P08246 1/20 0.35
CD69 Q07108 1/20 0.35
RXRA P19793 3/20 0.34
RXRB P28702 3/20 0.34
RXRG P48443 3/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ACHE P22303 1/20 0.33
CYP1A2 P05177 2/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5997682 0.84 HTR1D (0.37) ELANECD69RXRARXRBRXRG
SCHEMBL5995867 0.80 NR5A2 (0.33) NR5A2NR5A1GLRA3GLRBELANE
SCHEMBL14825538 0.72 GLRA3 (0.42) NR5A2NR5A1GLRA3GLRBRXRA
SCHEMBL6466602 0.72 GLRA3 (0.57) NR5A2NR5A1GLRA3GLRBELANE
SCHEMBL5996972 0.72 NR5A2 (0.31) NR5A2NR5A1CYP1A2CYP3A4CYP2C9
SCHEMBL28419884 0.71 GLRA3 (0.55) NR5A2NR5A1GLRA3GLRBELANE
SCHEMBL14988234 0.71 GLRA3 (0.41) NR5A2NR5A1GLRA3GLRBRXRA
SCHEMBL7219598 0.69 GLRA3 (0.39) NR5A2NR5A1GLRA3GLRBRXRA
SCHEMBL5997582 0.69 GLRA3 (0.36) NR5A2NR5A1GLRA3GLRBRXRA
SCHEMBL7225441 0.68 NR5A2 (0.42) NR5A2NR5A1GLRA3GLRBGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109250-B2 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2006-09-19 US disclosed
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-20050004247-A1 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. 2005-01-06 US disclosed
EP-1446410-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES Ciba SC Holding AG (CH) 2004-08-18 EP disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
WO-2003044030-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 NR5A2 15/4885NR5A1 10/4885GLRA3 458/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 NR5A2 25/4885NR5A1 176/4885GLRA3 1809/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 NR5A2 8/4885NR5A1 2/4885GLRA3 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.