Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217618 | 0.82 | NR5A2 (0.44) | NR5A2NR5A1HDAC1GLRA3GLRB | |
| SCHEMBL14825538 | 0.77 | GLRA3 (0.42) | NR5A2NR5A1GLRA3GLRBGABRA1 | |
| SCHEMBL6466602 | 0.77 | GLRA3 (0.57) | NR5A2NR5A1RAB9AGLRA3GLRB | |
| SCHEMBL7223640 | 0.75 | KCNK9 (0.55) | NR1H4RAB9AALOX5PTGS2MEN1 | |
| SCHEMBL28419884 | 0.75 | GLRA3 (0.55) | NR5A2NR5A1RAB9AGLRA3GLRB | |
| SCHEMBL10183617 | 0.75 | HDAC6 (0.53) | NR1H4EPHX2RAB9AHDAC1GABRA1 | |
| SCHEMBL14988234 | 0.75 | GLRA3 (0.41) | NR5A2NR5A1NR1H4EPHX2GLRA3 | |
| SCHEMBL7219598 | 0.73 | GLRA3 (0.39) | NR5A2NR5A1NR1H4EPHX2RAB9A | |
| SCHEMBL7217357 | 0.72 | LMNA (0.64) | NR1H4EPHX2RAB9AMEN1KMT2A | |
| SCHEMBL16147679 | 0.71 | GLRA3 (0.55) | NR5A2NR5A1GLRA3GLRBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |