Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773074 | 0.80 | NR5A2 (0.51) | GLRA3GLRBGABRA1GABRB2HTT | |
| SCHEMBL14825538 | 0.78 | GLRA3 (0.42) | GLRA3GLRBGABRA1GABRB2KMT2A | |
| SCHEMBL6466602 | 0.78 | GLRA3 (0.57) | GLRA3GLRBGABRA1GABRB2CYP2C19 | |
| SCHEMBL14988234 | 0.77 | GLRA3 (0.41) | GLRA3GLRBNR1H4EPHX2GABRA1 | |
| SCHEMBL28419884 | 0.77 | GLRA3 (0.55) | GLRA3GLRBGABRA1GABRB2CYP2C19 | |
| SCHEMBL5997582 | 0.75 | GLRA3 (0.36) | GLRA3GLRBGABRA1GABRB2CYP2C19 | |
| SCHEMBL7217663 | 0.73 | KMT2A (0.55) | NR1H4KMT2AALDH1A1HSP90AA1NPC1 | |
| SCHEMBL7225441 | 0.73 | NR5A2 (0.42) | GLRA3GLRBNR1H4EPHX2GABRA1 | |
| SCHEMBL7218380 | 0.73 | TP53 (0.41) | HTTNR5A2NR5A1ALDH1A1RAB9A | |
| SCHEMBL16147679 | 0.72 | GLRA3 (0.55) | GLRA3GLRBGABRA1GABRB2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |