Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998674 | 0.90 | NPSR1 (0.39) | NPSR1TSHRMAPK1AVPR1AALDH1A1 | |
| SCHEMBL5996174 | 0.87 | PIN1 (0.33) | TSHRMAPK1MAPTALDH1A1 | |
| SCHEMBL5998937 | 0.79 | NPSR1 (0.39) | NPSR1POLBTSHRMAPK1MAPT | |
| SCHEMBL5996055 | 0.77 | HPGD (0.37) | NPSR1TSHRMAPK1AVPR1AMAPT | |
| SCHEMBL5996858 | 0.73 | PIN1 (0.36) | NPSR1POLBTSHRMAPK1MAPT | |
| SCHEMBL5998111 | 0.72 | TNF (0.35) | NPSR1POLBAVPR1AMAPTALDH1A1 | |
| SCHEMBL5998821 | 0.71 | TDP1 (0.32) | POLBTSHRMAPT | |
| SCHEMBL5997107 | 0.71 | ALDH1A1 (0.40) | POLBAVPR1AMAPTALDH1A1 | |
| SCHEMBL5997630 | 0.71 | ALDH1A1 (0.40) | POLBTSHRMAPK1ALDH1A1 | |
| SCHEMBL5998273 | 0.70 | ALDH1A1 (0.37) | POLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | NPSR1 2849/4885POLB 1119/4885TSHR 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.