Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999178 | 0.88 | NPSR1 (0.45) | NPSR1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5997105 | 0.84 | KMT2A (0.40) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL5998955 | 0.82 | CASP3 (0.33) | ALDH1A1KDM4EHPGDRAB9AKMT2A | |
| SCHEMBL5997212 | 0.82 | NPSR1 (0.60) | NPSR1CYP3A4ALDH1A1MAPTRAB9A | |
| SCHEMBL5997644 | 0.79 | NPSR1 (0.34) | NPSR1ALDH1A1MAPTTSHRPOLB | |
| SCHEMBL5997974 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EHPGDRAB9A | |
| SCHEMBL5998941 | 0.71 | POLB (0.33) | NPSR1ALDH1A1MAPTTSHRPOLB | |
| SCHEMBL5998674 | 0.70 | NPSR1 (0.39) | NPSR1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5538378 | 0.69 | NPSR1 (0.54) | NPSR1ALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL5998367 | 0.68 | PIN1 (0.42) | ALDH1A1MAPTKDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | NPSR1 2849/4885CYP3A4 204/4885ALDH1A1 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.