Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997204 | 0.87 | FGFR1 (0.41) | MAPTL3MBTL1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL5998387 | 0.84 | ALDH1A1 (0.49) | MAPTL3MBTL1PIN1ALDH1A1MEN1 | |
| SCHEMBL5998931 | 0.82 | RGS4 (0.46) | TDP1PTPN1MMP8MAPTL3MBTL1 | |
| SCHEMBL5998838 | 0.78 | ALDH1A1 (0.38) | PTPN1MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL5998414 | 0.77 | MEN1 (0.43) | MAPTL3MBTL1PIN1ALDH1A1NPSR1 | |
| SCHEMBL5997105 | 0.76 | KMT2A (0.40) | TDP1MMP8MAPTPIN1ALDH1A1 | |
| SCHEMBL5998367 | 0.76 | PIN1 (0.42) | TDP1MAPTPIN1ALDH1A1MEN1 | |
| SCHEMBL5998418 | 0.76 | ALDH1A1 (0.46) | TDP1MAPTPIN1ALDH1A1MEN1 | |
| SCHEMBL5996615 | 0.74 | PIN1 (0.47) | L3MBTL1PIN1ALDH1A1MEN1NPC1 | |
| SCHEMBL5998122 | 0.74 | ANPEP (0.44) | MAPTL3MBTL1PIN1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | TDP1 3775/4885PTPN1 4172/4885MMP8 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.