Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998421 | 0.89 | RPS6KA2 (0.50) | ALOX5ALDH1A1KMT2APKMKDM4E | |
| SCHEMBL5997578 | 0.82 | PKM (0.47) | ALOX5ALDH1A1KMT2APKMKDM4E | |
| SCHEMBL5997416 | 0.81 | NPC1 (0.46) | ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL5998188 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5998277 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL5997021 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EL3MBTL1MEN1 | |
| SCHEMBL5998010 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2APKMMEN1 | |
| SCHEMBL14876485 | 0.79 | ALOX5 (0.56) | ALOX5ALDH1A1KMT2APKMKDM4E | |
| SCHEMBL5998841 | 0.78 | TNF (0.47) | ALDH1A1L3MBTL1TNF | |
| SCHEMBL15494462 | 0.78 | ALOX5 (0.58) | ALOX5ALDH1A1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | ALOX5 1211/4885ALDH1A1 216/4885KMT2A 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.