Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998070 | 0.89 | DPP7 (0.38) | DPP7SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5996628 | 0.85 | ALDH1A1 (0.39) | DPP7SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL5998686 | 0.83 | GABRG2 (0.39) | DPP7SMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL5998512 | 0.83 | GABRG2 (0.39) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL5995998 | 0.83 | GABRG2 (0.39) | DPP7MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5998148 | 0.81 | HDAC4 (0.35) | MAPTSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6006612 | 0.80 | KDM4E (0.50) | MAPTSMN1; SMN2TDP1ALDH1A1KMT2A | |
| SCHEMBL5998793 | 0.78 | SLC6A2 (0.34) | MAPTSMN1; SMN2MAPK1TDP1ALDH1A1 | |
| SCHEMBL5997427 | 0.74 | MEN1 (0.34) | DPP7MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2144236 | 0.74 | CA9 (0.46) | MAPTSMN1; SMN2TDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | DPP7 4062/4885MAPT 3262/4885SMN1; SMN2 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.