Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996628 | 0.88 | ALDH1A1 (0.39) | GABRG2GABRB3GABRA5TP53HSD17B3 | |
| SCHEMBL5998193 | 0.88 | HSD17B3 (0.38) | MDM2HSD17B3MAPTALDH1A1KMT2A | |
| SCHEMBL5998686 | 0.86 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5995998 | 0.86 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5998793 | 0.86 | SLC6A2 (0.34) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5998148 | 0.84 | HDAC4 (0.35) | L3MBTL1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL6006612 | 0.83 | KDM4E (0.50) | LMNAL3MBTL1MAPTHTTKDM4E | |
| SCHEMBL5998428 | 0.83 | DPP7 (0.41) | LMNAL3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5997427 | 0.78 | MEN1 (0.34) | TP53MDM2HSD17B3LMNAMAPT | |
| SCHEMBL5997031 | 0.74 | DPP9 (0.36) | MDM2HSD17B3LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | GABRG2 1543/4885GABRB3 1206/4885GABRA5 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.