Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL301979 | 0.98 | MAPT (0.33) | MAPTSMN1; SMN2CA1CA2CA9 | |
| Phosphoric Acid SCHEMBL580844 | 0.91 | MAPT (0.30) | MAPTSMN1; SMN2CA1CA2CA9 | |
| Pyrophosphoric Acid SCHEMBL301910 | 0.85 | FDPS (0.40) | — | |
| Phosphoric Acid SCHEMBL6254623 | 0.83 | MAPT (0.44) | MAPTSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL58211 | 0.83 | MAPT (0.42) | MAPTSMN1; SMN2CA1CA2CA9 | |
| Pyrophosphoric Acid SCHEMBL9244616 | 0.81 | FDPS (0.36) | — | |
| Phosphoric Acid SCHEMBL28034593 | 0.80 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2 | |
| Phosphoric Acid SCHEMBL5998742 | 0.80 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2 | |
| Phosphoric Acid SCHEMBL670321 | 0.80 | CYP1A2 (0.42) | SMN1; SMN2CYP1A2 | |
| Phosphoric Acid SCHEMBL10873614 | 0.80 | CYP1A2 (0.42) | SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132466-B2 | Halogen-free flame retardant compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-11-07 | — | — | US | disclosed |
| US-20040259986-A1 | Halogen-free flame retardant compounds | CIBA SPECIALTY CHEMICALS CORP. | 2004-12-23 | — | — | US | disclosed |
| EP-1434767-A1 | HALOGEN-FREE FLAME RETARDANT COMPOUNDS | Ciba SC Holding AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003031417-A1 | HALOGEN-FREE FLAME RETARDANT COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-17 | — | — | WO | disclosed |