Phosphoric Acid

Phosphoric Acid

SCHEMBL301979

NNc1nc(N)nc(N)n1.NNc1nc(N)nc(N)n1.NNc1nc(N)nc(N)n1.O=P(O)(O)O

nearest known ligand 0.33

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 1/20 0.32
CYP1A2 P05177 1/20 0.32
KDM4E B2RXH2 2/20 0.31
KDM5A P29375 1/20 0.31
JMJD1C Q15652 1/20 0.31
KDM3A Q9Y4C1 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL5998744 0.98 MAPT (0.32) MAPTSMN1; SMN2CA1CA2CA9
Phosphoric Acid SCHEMBL580844 0.94 MAPT (0.30) MAPTSMN1; SMN2CA1CA2CA9
Pyrophosphoric Acid SCHEMBL301910 0.87 FDPS (0.40) KDM4EKDM5AJMJD1CKDM3A
Phosphoric Acid SCHEMBL6254623 0.85 MAPT (0.44) MAPTSMN1; SMN2CA1CA2CA9
SCHEMBL58211 0.84 MAPT (0.42) MAPTSMN1; SMN2CA1CA2CA9
Pyrophosphoric Acid SCHEMBL9244616 0.82 FDPS (0.36) KDM4EKDM5AJMJD1CKDM3A
Phosphoric Acid SCHEMBL407305 0.82 CYP1A2 (0.42) SMN1; SMN2CYP1A2LMNA
Phosphoric Acid SCHEMBL10873614 0.82 CYP1A2 (0.42) SMN1; SMN2CYP1A2LMNA
Phosphoric Acid SCHEMBL670321 0.82 CYP1A2 (0.42) SMN1; SMN2CYP1A2LMNA
Phosphoric Acid SCHEMBL73239 0.82 CYP1A2 (0.42) SMN1; SMN2CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116355311-A Glass fiber reinforced polypropylene resin composition and molded article comprising the same 现代自动车株式会社 2023-06-30 CN claimed
US-20230203256-A1 GLASS FIBER REINFORCED POLYPROPYLENE RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME KIA CORPORATION (KR) 2023-06-29 US claimed
CN-114622306-A Production method of environment-friendly flame-retardant cable filling rope 武汉亮九通电缆材料有限公司 2022-06-14 CN claimed
CN-110092983-B Synergistic halogen-free flame retardant and application thereof, EPDM/PP thermoplastic elastomer and preparation method and application thereof 中国石油化工股份有限公司 2021-12-21 CN claimed
CN-112885501-A Halogen-free photovoltaic cable 广州番禺电缆集团有限公司 2021-06-01 CN claimed
CN-112724361-A Nitrogen-phosphorus-containing lignin-based intumescent flame retardant modified polyurethane elastomer and preparation method thereof 桐乡市昇威电子商务服务有限公司 2021-04-30 CN claimed
CN-111154142-A Hydrophobic flame retardant and preparation method thereof 安徽理工大学 2020-05-15 CN claimed
EP-2825589-B1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2020-05-06 EP claimed
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants BASF SE (DE) 2019-09-17 US claimed
CN-110092983-A Synergistic halogen-free flame retardants and its application and EPDM/PP thermoplastic elastomer (TPE) and its preparation method and application 中国石油化工股份有限公司 2019-08-06 CN claimed
EP-1751223-B1 FLAME RETARDANTS BASF SE (DE) 2009-08-12 EP claimed
JP-2007537321-A 2007-12-20 JP claimed
US-20070228343-A1 Flame Retardants CIBA SPECIALTY CHEMICALS CORP. 2007-10-04 US claimed
EP-1751223-A1 FLAME RETARDANTS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-14 EP claimed
US-20060138391-A1 Flame retardant composition comprising a phosphonic acid metal salt and a nitrogen containing compound CIBA SPECIALTY CHEMICALS CORP. 2006-06-29 US claimed
WO-2005113661-A1 FLAME RETARDANTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-12-01 WO claimed
EP-1563004-A1 FLAME RETARDANT COMPOSITION COMPRISING A PHOSPHONIC ACID METAL SALT AND A NITROGEN-CONTAINING COMPOUND Ciba SC Holding AG (CH) 2005-08-17 EP claimed
EP-1549708-A1 FLAME RETARDANT COMPOSITIONS Ciba SC Holding AG (CH) 2005-07-06 EP claimed
WO-2004046235-A1 FLAME RETARDANT COMPOSITION COMPRISING A PHOSPHONIC ACID METAL SALT AND A NITROGEN-CONTAINING COMPOUND CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-03 WO claimed
WO-2004031286-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants PFAS, PCBP1, DDT MAPT 248/4885SMN1; SMN2 732/4885CA1 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.