Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998960 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EMAPK10SYK | |
| SCHEMBL1165268 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EMAPK10SYK | |
| SCHEMBL7366516 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KDM4EHSP90AA1MAPT | |
| SCHEMBL18435536 | 0.74 | KDM4E (0.50) | SMN1; SMN2ALDH1A1KDM4EMAPK10SYK | |
| SCHEMBL31521530 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4EHSP90AA1MAPT | |
| SCHEMBL28406828 | 0.74 | MDM2 (0.44) | SMN1; SMN2ALDH1A1KDM4EHTTCYP1A2 | |
| SCHEMBL16462491 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4EHSP90AA1MAPT | |
| SCHEMBL18144294 | 0.72 | CA2 (0.44) | ALDH1A1MAPTBRD4 | |
| SCHEMBL1794244 | 0.72 | CA2 (0.44) | ALDH1A1MAPTBRD4 | |
| SCHEMBL3488827 | 0.71 | MME (0.45) | SMN1; SMN2ALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041670-B2 | Florfenicol-type antibiotics | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2006-05-09 | — | — | US | disclosed |
| US-20060014743-A1 | Methods of preventing bacterial infections with florfenicol-type antibiotics | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-01-19 | — | — | US | disclosed |
| EP-1487785-A2 | NOVEL FLORFENICOL-TYPE ANTIBIOTICS | Schering-Plough Ltd. (CH) | 2004-12-22 | — | — | EP | disclosed |
| US-20040082553-A1 | Novel florfenicol-type antibiotics | INTERVET INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2003077828-A2 | NOVEL FLORFENICOL-TYPE ANTIBIOTICS | SCHERING-PLOUGH, LTD. (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082553-A1 | Novel florfenicol-type antibiotics | Q6ZSR9, FOS, FABP2 | SMN1; SMN2 3436/4885ALDH1A1 2683/4885KDM4E 2247/4885 |
| US-20060014743-A1 | Methods of preventing bacterial infections with florfenicol-type antibiotics | FOS, FABP2, NISCH | SMN1; SMN2 2895/4885ALDH1A1 2335/4885KDM4E 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.