Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999404 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNAFPR1CNR2FAAH | |
| SCHEMBL5999113 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNAFPR1CNR2FAAH | |
| SCHEMBL1077288 | 0.65 | MAPK1 (0.40) | ALDH1A1FPR1CNR2TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL1077516 | 0.63 | SMN1; SMN2 (0.39) | ALDH1A1FPR1CNR2TSHRMAPK1 | |
| SCHEMBL5999177 | 0.62 | ALDH1A1 (0.39) | ALDH1A1LMNAFPR1CNR2FAAH | |
| SCHEMBL17476011 | 0.60 | LMNA (0.47) | ALDH1A1LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL1073193 | 0.60 | ALDH1A1 (0.56) | ALDH1A1LMNAFPR1MAPK1SMN1; SMN2 | |
| SCHEMBL2998694 | 0.58 | FPR1 (0.38) | ALDH1A1LMNAFPR1TSHRMAPK1 | |
| SCHEMBL2998699 | 0.58 | FPR1 (0.38) | ALDH1A1LMNAFPR1TSHRMAPK1 | |
| SCHEMBL2386636 | 0.57 | USP2 (0.51) | ALDH1A1LMNATSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-20060194779-A1 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194779-A1 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | CNR1, CNR2, HRH4 | ALDH1A1 1715/4885LMNA 3868/4885FPR1 1546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.