Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.87 |
| ▸ | MAOB | P27338 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119689 | 0.93 | PARP10 (1.00) | PARP10MAOBNR4A1NR4A2NR4A3 | |
| Hydrochloric Acid SCHEMBL8861530 | 0.91 | PARP10 (0.97) | PARP10MAOBALDH1A1MAPTNR4A1 | |
| SCHEMBL1750167 | 0.85 | NR4A2 (0.86) | ALDH1A1MAPTNR4A1NR4A2NR4A3 | |
| SCHEMBL11117974 | 0.83 | PARP10 (0.83) | PARP10MAOBALDH1A1MAPTNR4A2 | |
| SCHEMBL12339549 | 0.83 | PARP10 (0.83) | PARP10MAOBALDH1A1MAPTPARP1 | |
| SCHEMBL13513249 | 0.82 | MAOB (0.87) | MAOBALDH1A1MAPTNR4A1NR4A2 | |
| SCHEMBL1387246 | 0.81 | NR4A2 (0.77) | PARP10MAOBNR4A2MEN1KMT2A | |
| SCHEMBL19980221 | 0.81 | F10 (0.72) | PARP10MAOBNR4A2RAB9ARXFP1 | |
| SCHEMBL4338622 | 0.81 | MAOB (0.74) | PARP10MAOBNR4A2 | |
| SCHEMBL14533430 | 0.81 | PARP10 (0.63) | PARP10MAOBALDH1A1MAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060047123-A1 | Mercaptoamides as histone deacetylase inhibitors | AHMED SALEH | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047123-A1 | Mercaptoamides as histone deacetylase inhibitors | HDAC1, HDAC11, HDAC2 | PARP10 1205/4885MAOB 870/4885ALDH1A1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.