SCHEMBL13513249

SCHEMBL13513249

CC(=O)c1ccc(COc2ccccc2)cc1

nearest known ligand 0.87

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.87
ALDH1A1 P00352 2/20 0.82
HTT P42858 1/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
L3MBTL1 Q9Y468 1/20 0.82
MAOA P21397 2/20 0.71
MAPT P10636 1/20 0.66
NR4A1 P22736 1/20 0.64
NR4A2 P43354 1/20 0.64
NR4A3 Q92570 1/20 0.64
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
RXFP1 Q9HBX9 1/20 0.62
HRH3 Q9Y5N1 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11845043 0.94 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL42302 0.93 MAOB (1.00) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL29154487 0.90 ALDH1A1 (0.83) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL6054433 0.90 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL6337667 0.88 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL9126144 0.88 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL27518404 0.85 MAOB (0.85) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL1750167 0.85 NR4A2 (0.86) ALDH1A1SMN1; SMN2MAPTNR4A1NR4A2
SCHEMBL17602370 0.84 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL933577 0.84 MAOB (0.76) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220098159-A1 CARBAMATE DERIVATIVES AND USES THEREOF NodThera Limited (GB) 2022-03-31 US disclosed
CN-113660983-A Carbamate derivatives and uses thereof 诺瑟拉有限公司 2021-11-16 CN disclosed
WO-2020152361-A1 CARBAMATE DERIVATIVES AND USES THEREOF NodThera Limited (GB) 2020-07-30 WO disclosed
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20090109379-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM COPORATION (JP) 2009-04-30 US disclosed
US-20090109379-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM COPORATION (JP) 2009-04-30 US disclosed
US-20070259134-A1 Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070259134-A1 Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
WO-2007111388-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220098159-A1 CARBAMATE DERIVATIVES AND USES THEREOF CASP1, IL1B, PYCARD MAOB 3295/4885ALDH1A1 617/4885HTT 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.