Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514761 | 0.80 | TDP1 (0.53) | TDP1CASP3PDE4APDE4BPDE4C | |
| SCHEMBL5514759 | 0.80 | TDP1 (0.53) | TDP1CASP3PDE4APDE4BPDE4C | |
| SCHEMBL14583742 | 0.75 | CASP3 (0.41) | TDP1CASP3PDE4APDE4BPDE4C | |
| SCHEMBL8555666 | 0.70 | TDP1 (0.49) | TDP1MAPTALDH1A1LMNAGAA | |
| SCHEMBL19588472 | 0.69 | TDP1 (0.62) | TDP1CASP3PDE4APDE4BPDE4C | |
| SCHEMBL6364898 | 0.68 | TDP1 (0.52) | TDP1CASP3ALDH1A1LMNAKDM4E | |
| SCHEMBL6716400 | 0.67 | HPGD (0.55) | TDP1CASP3MAPTALDH1A1HPGD | |
| SCHEMBL13108155 | 0.67 | TDP1 (0.48) | TDP1CASP3MAPTALDH1A1LMNA | |
| SCHEMBL27755640 | 0.67 | TDP1 (0.65) | TDP1CASP3PDE4APDE4BPDE4C | |
| SCHEMBL5518871 | 0.66 | TDP1 (0.42) | TDP1CASP3MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178425-A1 | FUNGICIDAL CARBOXAMIDES | BASARAB GREGORY S | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178425-A1 | FUNGICIDAL CARBOXAMIDES | CBR3, CBR1, CYC1 | TDP1 877/4885CASP3 82/4885PDE4A 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.