Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818672 | 0.94 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL29677813 | 0.83 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL2804157 | 0.83 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL20842529 | 0.81 | PSEN1 (0.53) | KDM4ECNR2PSEN1PSEN2APH1B | |
| SCHEMBL28225833 | 0.80 | ALDH1A1 (0.80) | ALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL601808 | 0.79 | CNR2 (0.59) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL600012 | 0.78 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL12184494 | 0.78 | CNR2 (0.68) | ALDH1A1HPGDCNR2PSEN1PSEN2 | |
| SCHEMBL600075 | 0.78 | CNR2 (0.72) | ALDH1A1HPGDKDM4EHSD17B10CNR2 | |
| SCHEMBL28007398 | 0.77 | CNR2 (0.64) | CNR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060073357-A1 | Carbazole compounds and use of such compounds in organic electroluminiscent devices | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2006-04-06 | — | — | US | disclosed |
| EP-1594939-A2 | CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES | Koninklijke Philips Electronics N.V. (NL) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072205-A2 | CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2004-08-26 | — | — | WO | disclosed |