SCHEMBL600002

SCHEMBL600002

C[C@@H](C(=O)OC(c1cccc2ccccc12)c1cccc2ccccc12)c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 2/20 0.44
ACP3 P15309 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
IDH1 O75874 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ALDH1A1 P00352 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599730 0.89 ALDH1A1 (0.47) CYP2C19SLC6A4ALDH1A1PTGS2
SCHEMBL598815 0.88 RAB9A (0.39) ALDH1A1
SCHEMBL17681452 0.87 ALDH1A1 (0.39) ALDH1A1PTGS2
SCHEMBL606226 0.86 TDP1 (0.48) ALDH1A1PTGS2
SCHEMBL598171 0.85 UTS2R (0.38) UTS2RACP3ALDH1A1PTGS2
SCHEMBL17681440 0.84 MEN1 (0.46) CYP1A2CYP2C19ALDH1A1
SCHEMBL17681403 0.84 TDP1 (0.49) ACP3CYP1A2PTGS2
SCHEMBL17681446 0.84 KDM4E (0.40) CYP1A2ALDH1A1
SCHEMBL17681434 0.84 IDH1 (0.38) ACP3IDH1
SCHEMBL17681443 0.82 AKR1C3 (0.41) CYP1A2CYP2C19ALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315442-B2 Method for manufacturing optically active carboxylic acid ester TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2016-04-19 US disclosed
US-8115008-B2 Method for producing optically active ester and method for producing optically active carboxylic acid TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2012-02-14 US disclosed