Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.40 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000180 | 0.84 | HTR2A (0.61) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL6000147 | 0.82 | HTR2A (0.43) | HTR2ASLC6A4KCNH2ADRB2SOS1 | |
| SCHEMBL6000303 | 0.75 | ADRB2 (0.51) | HTR2ASLC6A4KCNH2ADRB2 | |
| SCHEMBL5998632 | 0.74 | NOS1 (0.51) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL14751312 | 0.74 | CYP1A2 (0.43) | GLRA3GLRBSCN9ATRPM5MAOA | |
| SCHEMBL13106151 | 0.72 | KMO (0.51) | GLRA3GLRBTRPM5MAOAMAOB | |
| SCHEMBL12328667 | 0.72 | MAP4K4 (0.40) | HTR2ASLC6A4KCNH2SCN9A | |
| SCHEMBL5999729 | 0.71 | AHR (0.49) | HTR2ASLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL2450168 | 0.71 | MAP4K4 (0.40) | HTR2ASLC6A4KCNH2SCN9A | |
| SCHEMBL5999735 | 0.71 | HTR2A (0.41) | HTR2ASLC6A4KCNH2SOS1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | HTR2A 7/4885SLC6A4 150/4885KCNH2 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.