Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508422 | 0.83 | DRD2 (0.48) | UBE2MDCUN1D1 | |
| SCHEMBL5923658 | 0.83 | DRD2 (0.48) | — | |
| SCHEMBL4768518 | 0.81 | DRD2 (0.47) | CCR5 | |
| SCHEMBL4775934 | 0.80 | ADRA1D (0.55) | — | |
| SCHEMBL5923679 | 0.79 | DRD2 (0.44) | — | |
| SCHEMBL5888061 | 0.79 | DRD2 (0.51) | — | |
| SCHEMBL5888375 | 0.78 | UBE2M (0.40) | UBE2MDCUN1D1CCR5 | |
| SCHEMBL5923766 | 0.78 | DRD2 (0.41) | CCR5 | |
| SCHEMBL5888272 | 0.77 | DRD2 (0.44) | CCR5 | |
| SCHEMBL4775593 | 0.75 | ADRA1D (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060217418-A1 | Substituted alkyl amido piperidines | H. LUNDBECK A/S (DK) | 2006-09-28 | — | — | US | disclosed |
| US-20040186103-A1 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217418-A1 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | UBE2M 3996/4885DCUN1D1 602/4885CCR5 230/4885 |
| US-20040186103-A1 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | UBE2M 3996/4885DCUN1D1 602/4885CCR5 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.