SCHEMBL6000610

SCHEMBL6000610

CC(C)(C)CCOc1cc(OCCC(C)(C)C)cc(-c2c3nc(c(Br)c4ccc([nH]4)c(-c4cc(OCCC(C)(C)C)cc(OCCC(C)(C)C)c4)c4nc(cc5ccc2[nH]5)C=C4)C=C3)c1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.43
▸ STAT1 P42224 1/20 0.43
▸ TERT O14746 3/20 0.32
▸ TOP1 P11387 2/20 0.30
▸ ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6713137 0.92 STAT3 (0.50) STAT3STAT1TERTTOP1
SCHEMBL6002479 0.91 TERT (0.38) TERTTOP1ABCG2
SCHEMBL14841921 0.78 STAT3 (0.50) STAT3STAT1TERTTOP1
SCHEMBL29395084 0.78 STAT3 (0.50) STAT3STAT1TERT
SCHEMBL28879055 0.77 STAT3 (0.49) STAT3STAT1TERT
SCHEMBL6711729 0.77 STAT3 (0.49) STAT3STAT1TERTABCG2
SCHEMBL29397238 0.77 TERT (0.40) TERTTOP1ABCG2
SCHEMBL28702500 0.77 TERT (0.40) TERTTOP1ABCG2
SCHEMBL5134031 0.76 STAT3 (0.74) STAT3STAT1TERTTOP1ABCG2
SCHEMBL2940532 0.76 STAT3 (0.74) STAT3STAT1TERTTOP1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363916-A4 EMISSIVE MULTICHROMOPHORIC SYSTEMS UNIV PENNSYLVANIA (US) 2006-06-28 — — EP disclosed
US-20040067198-A1 Emissive multichromophoric systems THERIEN MICHAEL J (US) 2004-04-08 — — US disclosed
EP-1363916-A2 EMISSIVE MULTICHROMOPHORIC SYSTEMS The Trustees of The University of Pennsylvania (US) 2003-11-26 — — EP disclosed
WO-2002104072-A2 EMISSIVE MULTICHROMOPHORIC SYSTEMS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-12-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067198-A1 Emissive multichromophoric systems MC3R, EML4, TYR STAT3 2744/4885STAT1 4583/4885TERT 1534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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