SCHEMBL6002479

SCHEMBL6002479

CC(C)(C)CCOc1cc(OCCC(C)(C)C)cc(-c2c3nc(c(Br)c4ccc([nH]4)c(-c4cc(OCCC(C)(C)C)cc(OCCC(C)(C)C)c4)c4nc(c(Br)c5ccc2[nH]5)C=C4)C=C3)c1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.38
▸ TOP1 P11387 4/20 0.34
▸ ABCG2 Q9UNQ0 1/20 0.34
▸ CYCS P99999 3/20 0.34
▸ ENPP2 Q13822 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6000610 0.91 STAT3 (0.43) TERTTOP1ABCG2
SCHEMBL28702500 0.84 TERT (0.40) TERTTOP1ABCG2CYCS
SCHEMBL29397238 0.84 TERT (0.40) TERTTOP1ABCG2CYCS
SCHEMBL6002170 0.83 TERT (0.40) TERTTOP1ABCG2CYCSENPP2
SCHEMBL6713137 0.81 STAT3 (0.50) TERTTOP1
SCHEMBL5013770 0.75 TERT (0.44) TERTTOP1ABCG2CYCSENPP2
SCHEMBL30831251 0.75 TERT (0.44) TERTTOP1ABCG2CYCSENPP2
SCHEMBL21976863 0.73 TERT (0.48) TERTTOP1ABCG2CYCSENPP2
SCHEMBL17687648 0.72 TERT (0.43) TERTABCG2
SCHEMBL498495 0.72 TERT (0.51) TERTTOP1ABCG2CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363916-A4 EMISSIVE MULTICHROMOPHORIC SYSTEMS UNIV PENNSYLVANIA (US) 2006-06-28 — — EP disclosed
US-20040067198-A1 Emissive multichromophoric systems THERIEN MICHAEL J (US) 2004-04-08 — — US disclosed
EP-1363916-A2 EMISSIVE MULTICHROMOPHORIC SYSTEMS The Trustees of The University of Pennsylvania (US) 2003-11-26 — — EP disclosed
WO-2002104072-A2 EMISSIVE MULTICHROMOPHORIC SYSTEMS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-12-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067198-A1 Emissive multichromophoric systems MC3R, EML4, TYR TERT 1534/4885TOP1 2833/4885ABCG2 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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