SCHEMBL6000988

SCHEMBL6000988

NN(N)S(=O)(=O)N(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.48
ESR1 P03372 1/20 0.45
CA2 P00918 4/20 0.39
CA9 Q16790 4/20 0.39
CA12 O43570 3/20 0.39
CA1 P00915 2/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
PLA2G7 Q13093 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
ALDH1A1 P00352 4/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALOX15 P16050 1/20 0.37
HSP90AA1 P07900 1/20 0.36
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129629 0.84 PKM (0.56) PKMESR1CA2CA9CA12
SCHEMBL132005 0.77 PKM (0.50) PKMESR1CA2CA9CA12
SCHEMBL450584 0.72 ESR1 (0.52) PKMESR1CA2CA9CA12
SCHEMBL5500613 0.72 PKM (0.50) PKMESR1CA2CA9CA12
SCHEMBL10632559 0.72 PKM (0.50) PKMESR1CA2CA9CA12
SCHEMBL1704542 0.72 PKM (0.50) PKMESR1CA2CA9CA12
SCHEMBL11595292 0.72 PKM (0.50) PKMESR1CA2CA9CA12
SCHEMBL6562774 0.72 ESR1 (0.43) PKMESR1ALDH1A1NPSR1HSP90AA1
SCHEMBL5665562 0.71 PKM (0.45) PKMESR1CA2CA9CA12
SCHEMBL812682 0.70 PKM (0.79) PKMESR1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1682717-A1 METHOD FOR THE REACTIVE COLOURING OF LEATHER BASF Aktiengesellschaft (DE) 2006-07-26 EP disclosed
WO-2005040490-A1 METHOD FOR THE REACTIVE COLOURING OF LEATHER BASF AKTIENGESELLSCHAFT (DE) 2005-05-06 WO disclosed