SCHEMBL812682

SCHEMBL812682

O=S(=O)(c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.79
ESR1 P03372 2/20 0.73
APOBEC3G Q9HC16 1/20 0.56
ALDH1A1 P00352 4/20 0.53
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
KMT2A Q03164 1/20 0.48
HTR6 P50406 1/20 0.48
LMNA P02545 1/20 0.46
HDAC6 Q9UBN7 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
PLA2G7 Q13093 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634601 0.88 ALDH1A1 (0.66) PKMESR1ALDH1A1CA12CA9
SCHEMBL8656925 0.88 PKM (0.63) PKMESR1APOBEC3GALDH1A1CA12
SCHEMBL3702995 0.85 ALDH1A1 (0.63) PKMESR1APOBEC3GALDH1A1CA12
SCHEMBL2114599 0.85 ESR1 (1.00) PKMESR1ALDH1A1CA12CA9
SCHEMBL3697451 0.85 PKM (0.71) PKMESR1ALDH1A1CA12CA9
SCHEMBL8976129 0.85 PKM (0.71) PKMESR1ALDH1A1CA12CA9
SCHEMBL6678557 0.85 PKM (0.66) PKMESR1APOBEC3GALDH1A1CA12
SCHEMBL8658317 0.84 PKM (0.59) PKMESR1APOBEC3GALDH1A1CA12
SCHEMBL8663009 0.83 PKM (0.58) PKMESR1APOBEC3GALDH1A1CA12
SCHEMBL8662905 0.83 PKM (0.58) PKMESR1APOBEC3GALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4228262-A SULFUR COMPOUND ALUMINUM CHLORIDE-TITANIUM CHLORIDE COMPLEX POLYMERIZATION CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-10-14 US claimed
US-4161461-A OLEFIN COORDINATION-POLYMERIZATION CATALYST; TRANSITION METAL HALIDE TREATED WITH ORGANIC SULFONE, SULFONAMIDE OR SULFIDE AND GRINDED WITH ALUMINUM AND TITANIUM CHLORIDES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-17 US claimed
CN-119269811-A Neuroactive steroids, compositions, and uses thereof 萨奇治疗股份有限公司 2025-01-07 CN disclosed
CN-119192267-A Neuroactive steroids, compositions, and uses thereof 萨奇治疗股份有限公司 2024-12-27 CN disclosed
CN-119192266-A 3, 3-Disubstituted 19-norpregnane compounds, compositions, and uses thereof 萨奇治疗股份有限公司 2024-12-27 CN disclosed
CN-113956315-B Neuroactive steroids, compositions, and uses thereof 萨奇治疗股份有限公司 2024-08-09 CN disclosed
CN-113444086-B Ezh2 inhibitors and uses thereof 达纳-法伯癌症研究所股份有限公司 2024-04-30 CN disclosed
CN-117924310-A Macrocyclic compounds and uses thereof 哈佛大学的校长及成员们 2024-04-26 CN disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
CN-106496373-B Catalytic component and its preparation and application for olefinic polymerization 中国石油化工股份有限公司 2019-09-27 CN disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-5612398-A Radiation-resistant polycarbonates BAYER AG (DE) 1997-03-18 US disclosed
EP-0664321-A1 Polycarbonates stabilized against radiation BAYER AG (DE) 1995-07-26 EP disclosed
US-4400301-A COORDINATION CATALYST OF ALUMINUM CHLORIDE, TITANIUM TETRACHLORIDE AND A LEWIS BASE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-23 US disclosed
US-4354010-A OLEFIN POLYMERIZATION CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-10-12 US disclosed
US-4243782-A POLYMERIZATION CATALYSTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-01-06 US disclosed
US-4228262-A SULFUR COMPOUND ALUMINUM CHLORIDE-TITANIUM CHLORIDE COMPLEX POLYMERIZATION CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-10-14 US disclosed
US-4193893-A GRINDING METAL COMPOUND WITH A CARBOXYLIC ACID OR ESTER AND AN ORGANO-LEWIS BASE; POLYMERIZATION CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-18 US disclosed
US-4161461-A OLEFIN COORDINATION-POLYMERIZATION CATALYST; TRANSITION METAL HALIDE TREATED WITH ORGANIC SULFONE, SULFONAMIDE OR SULFIDE AND GRINDED WITH ALUMINUM AND TITANIUM CHLORIDES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-17 US disclosed
US-4111834-A Process for preparing a transition metal compound and it's use as a component in an olefin polymerization catalyst IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-09-05 US disclosed