Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000987 | 0.85 | PTGS1 (0.55) | PTGS1PTGS2PTPN1PPARGSTK39 | |
| SCHEMBL4976180 | 0.84 | PTGS1 (0.73) | PTGS1PTGS2MAPTALDH1A1GAA | |
| SCHEMBL11268431 | 0.79 | PTGS1 (0.46) | PTGS1PTGS2PTPN1PPARGMAPT | |
| SCHEMBL7524156 | 0.76 | PTPN1 (0.63) | PTGS1PTGS2PTPN1PPARGSMN1; SMN2 | |
| SCHEMBL25802435 | 0.74 | PTPN1 (0.49) | PTGS1PTGS2PTPN1SMN1; SMN2CYP3A4 | |
| SCHEMBL28994364 | 0.74 | PTGS1 (0.50) | PTGS1PTGS2MAPTALDH1A1MEN1 | |
| SCHEMBL11330348 | 0.73 | CA2 (0.67) | PTGS1PTGS2HPGDCA2 | |
| SCHEMBL7186092 | 0.72 | TTR (0.75) | MAPTALDH1A1MEN1GAAKMT2A | |
| SCHEMBL3528482 | 0.71 | ACLY (0.54) | PTGS1PTGS2PTPN1PPARGSMN1; SMN2 | |
| SCHEMBL1411551 | 0.70 | PTGS1 (0.46) | PTGS1PTGS2MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | ELANE, CTRL, PIGO | PTGS1 296/4885PTGS2 1435/4885PTPN1 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.