Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001211 | 0.85 | MAPT (0.40) | CYP19A1DHODHMAPTTDP1KDM4E | |
| SCHEMBL6001175 | 0.81 | PDE5A (0.48) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6001916 | 0.80 | MEN1 (0.43) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3452785 | 0.75 | HSD17B10 (0.45) | MAPTTDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28231738 | 0.68 | CYP19A1 (0.58) | CYP19A1DHODHKDM4EMEN1KMT2A | |
| SCHEMBL4133791 | 0.67 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL14323090 | 0.67 | PDE5A (0.34) | MAPTNPSR1 | |
| SCHEMBL8657096 | 0.66 | TOP1 (0.63) | CYP19A1DHODHMAPTTDP1KDM4E | |
| SCHEMBL3452690 | 0.65 | TSHR (0.38) | MAPTKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL6001383 | 0.65 | ALDH1A1 (0.51) | MAPTTDP1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | CYP19A1 863/4885DHODH 855/4885MAPT 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.