Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 10/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001578 | 0.91 | GNRHR (0.58) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5999615 | 0.91 | GNRHR (0.61) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5503850 | 0.91 | GNRHR (0.57) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5511248 | 0.90 | GNRHR (0.63) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5512568 | 0.90 | GNRHR (0.63) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5507824 | 0.90 | GNRHR (0.62) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5508081 | 0.89 | GNRHR (0.61) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5506315 | 0.89 | GNRHR (0.61) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5504511 | 0.89 | GNRHR (0.56) | GNRHRDRD2DRD3PARP1DHODH | |
| SCHEMBL5508203 | 0.88 | GNRHR (0.58) | GNRHRDRD2DRD3PARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111355-A1 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2006-05-25 | — | — | US | claimed |
| US-20060111355-A1 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111355-A1 | Gonadotropin releasing hormone receptor antagonists | GNRHR, LHCGR, GHRHR | GNRHR 1/4885DRD2 740/4885DRD3 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.