Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 12/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677474 | 0.88 | MTNR1B (0.57) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL5871250 | 0.86 | MTNR1B (0.64) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL6405872 | 0.86 | MTNR1B (0.55) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL5871858 | 0.85 | MTNR1B (0.86) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL6531816 | 0.83 | MTNR1B (0.55) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL8649814 | 0.83 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL8655497 | 0.82 | MTNR1B (0.79) | MTNR1BMTNR1A | |
| SCHEMBL6001733 | 0.81 | MTNR1B (0.50) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL6422049 | 0.81 | MTNR1B (0.73) | MTNR1BMTNR1A | |
| SCHEMBL5872403 | 0.81 | MTNR1B (0.56) | MTNR1BMTNR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1603395-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080170-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | CBR3, L3MBTL3, BRS3 | MTNR1B 1920/4885MTNR1A 1608/4885SIGMAR1 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.