SCHEMBL6001675

SCHEMBL6001675

Sc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
LMNA P02545 1/20 0.33
KCNN4 O15554 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27875145 0.97 TSHR (0.38) TSHRLMNAKCNN4CYP3A4MAPK1
SCHEMBL27858532 0.97 TSHR (0.38) TSHRLMNAKCNN4CYP3A4MAPK1
SCHEMBL27305380 0.79 ALDH1A1 (0.36) TSHRLMNATDP1
SCHEMBL545083 0.78 TSHR (0.50) TSHRLMNAKCNN4CYP3A4MAPK1
SCHEMBL30318973 0.78 TSHR (0.50) TSHRLMNAKCNN4CYP3A4MAPK1
Benzene SCHEMBL21048983 0.76 TSHR (0.56) TSHRLMNAKCNN4CYP3A4MAPK1
SCHEMBL3899036 0.75 TSHR (0.44) TSHRKCNN4MAPK1MAPTHDAC8
SCHEMBL72183 0.74 ALDH1A1 (0.44) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL29427756 0.74 ALDH1A1 (0.44) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL6565488 0.74 ALDH1A1 (0.44) TSHRLMNACYP3A4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110305143-A A kind of furans [2,3-c] and pyridine derivate and its preparation method and application 济南新科医药科技有限公司 2019-10-08 CN disclosed
CN-103446720-B Golf ball 邓禄普体育用品株式会社 2017-05-10 CN disclosed
CN-103446725-B Golf 邓禄普体育用品株式会社 2016-08-10 CN disclosed
CN-103418115-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-05-11 CN disclosed
CN-103418116-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-05-04 CN disclosed
CN-103372285-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-04-20 CN disclosed
CN-105381573-A GOLF BALL DUNLOP SPORTS CO LTD 2016-03-09 CN disclosed
CN-103446722-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446721-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446723-B Golf DUNLOP SPORTS CO., LTD. (JP) 2015-11-18 CN disclosed
CN-103446722-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 CN disclosed
CN-103418115-A Golf ball DUNLOP SPORTS CO LTD 2013-12-04 CN disclosed
CN-103418116-A Golf ball DUNLOP SPORTS CO LTD 2013-12-04 CN disclosed
CN-103372285-A Golf ball DUNLOP SPORTS CO LTD 2013-10-30 CN disclosed
CN-103182165-A Golf ball DUNLOP SPORTS CO LTD 2013-07-03 CN disclosed
CN-102989132-A Golf ball DUNLOP SPORTS CO LTD 2013-03-27 CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-20060281587-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed