Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594770 | 0.96 | CYP4A11 (0.43) | CYP4A11LOXL2CYP4F2ALDH1A1RAB9A | |
| SCHEMBL6138542 | 0.87 | CYP4Z1 (0.41) | CYP4A11LOXL2CYP4F2ALDH1A1RAB9A | |
| SCHEMBL9442229 | 0.86 | POLB (0.45) | CYP4A11LOXL2CYP4F2ALDH1A1RAB9A | |
| SCHEMBL3016468 | 0.83 | CYP4A11 (0.53) | CYP4A11LOXL2CYP4F2ALDH1A1MAPT | |
| SCHEMBL3596235 | 0.82 | LOXL2 (0.47) | CYP4A11LOXL2CYP4F2ALDH1A1MAPT | |
| SCHEMBL2294361 | 0.82 | CYP4A11 (0.43) | CYP4A11LOXL2CYP4F2ALDH1A1MAPT | |
| SCHEMBL6000361 | 0.80 | FOLH1 (0.54) | CYP4A11LOXL2CYP4F2ALDH1A1RAB9A | |
| SCHEMBL6000353 | 0.80 | CYP4A11 (0.49) | CYP4A11LOXL2CYP4F2ALDH1A1RAB9A | |
| SCHEMBL3594773 | 0.79 | SMN1; SMN2 (0.44) | CYP4A11CYP4F2RAB9AMAPTGAA | |
| SCHEMBL9442221 | 0.79 | CYP4A11 (0.42) | CYP4A11LOXL2CYP4F2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |
| EP-1216222-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019776-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |