Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594773 | 0.93 | SMN1; SMN2 (0.44) | CYP4Z1KDM4ECYP4A11KMT2ARAB9A | |
| SCHEMBL3594770 | 0.90 | CYP4A11 (0.43) | KDM4EALDH1A1CYP4A11RAB9ASMN1; SMN2 | |
| SCHEMBL6001848 | 0.87 | CYP4A11 (0.44) | KDM4EALDH1A1CYP4A11RAB9ASMN1; SMN2 | |
| SCHEMBL9442229 | 0.85 | POLB (0.45) | KDM4EALDH1A1CYP4A11RAB9ALOXL2 | |
| SCHEMBL2294774 | 0.81 | CYP4Z1 (0.39) | CYP4Z1ALDH1A1CYP4A11RAB9ACYP4F11 | |
| SCHEMBL3592364 | 0.81 | LTA4H (0.40) | KDM4EALDH1A1CYP4A11RAB9ASMN1; SMN2 | |
| SCHEMBL2294361 | 0.80 | CYP4A11 (0.43) | KDM4EALDH1A1CYP4A11KMT2ASMN1; SMN2 | |
| SCHEMBL3016468 | 0.79 | CYP4A11 (0.53) | ALDH1A1CYP4A11LOXL2CYP4F2TDP1 | |
| SCHEMBL3596235 | 0.77 | LOXL2 (0.47) | KDM4EALDH1A1CYP4A11KMT2ASMN1; SMN2 | |
| SCHEMBL4547658 | 0.77 | CYP1A2 (0.39) | CYP4Z1ALDH1A1CYP4A11KMT2ACYP4F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216223-B1 | NOVEL DICARBOXYLIC ACID DERIVATIVES WITH PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-11-09 | — | — | EP | disclosed |