Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129286 | 0.93 | HCAR3 (0.52) | MAPTTDP1MAPK1MEN1KMT2A | |
| SCHEMBL128849 | 0.88 | KMT2A (0.53) | MAPTTDP1MAPK1GAAMEN1 | |
| SCHEMBL30128459 | 0.88 | KMT2A (0.53) | MAPTTDP1MAPK1GAAMEN1 | |
| SCHEMBL19030004 | 0.84 | TDP1 (0.49) | MAPTTDP1MAPK1GAAMEN1 | |
| SCHEMBL2838098 | 0.81 | CRHBP (0.43) | MAPTTDP1MAPK1GAAMEN1 | |
| SCHEMBL28558294 | 0.80 | HCAR3 (0.51) | MAPTTDP1MAPK1KMT2ACRHBP | |
| SCHEMBL4626839 | 0.78 | TSHR (0.53) | GAACRHBPCRHR2HCAR3ALDH1A1 | |
| SCHEMBL1888218 | 0.78 | HCAR3 (0.54) | MAPTMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL6156984 | 0.78 | CRHBP (0.65) | MAPTTDP1MAPK1GAAMEN1 | |
| SCHEMBL688641 | 0.77 | HCAR3 (0.52) | MAPTMEN1KMT2ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006087194-A2 | DYE COMPOSITION COMPRISING AN OXONOL TYPE METHINE DIRECT DYE, PROCESS FOR IMPLEMENTATION AND USES THEREOF | L'OREAL (FR) | 2006-08-24 | — | — | WO | disclosed |