Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001852 | 0.93 | MAPT (0.51) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 | |
| SCHEMBL28558294 | 0.86 | HCAR3 (0.51) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 | |
| SCHEMBL1888218 | 0.84 | HCAR3 (0.54) | HCAR3ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL4626839 | 0.84 | TSHR (0.53) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 | |
| SCHEMBL6156984 | 0.84 | CRHBP (0.65) | HCAR3ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL10894653 | 0.83 | HCAR3 (0.56) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 | |
| SCHEMBL688641 | 0.83 | HCAR3 (0.52) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 | |
| SCHEMBL9760045 | 0.83 | HCAR3 (0.49) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 | |
| SCHEMBL211067 | 0.83 | ALDH1A1 (0.51) | HCAR3ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL17846944 | 0.83 | L3MBTL1 (0.54) | HCAR3ALDH1A1CRHBPCRHR2KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240350386-A1 | Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents | WELLA GERMANY GMBH (DE) | 2024-10-24 | — | — | US | claimed |
| US-12036299-B2 | Compositions containing direct dyes for imparting color and tone to the hair | L'OREAL (FR) | 2024-07-16 | — | — | US | claimed |
| EP-4362902-A1 | COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR | L'OREAL (FR) | 2024-05-08 | — | — | EP | claimed |
| CN-115980205-A | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product | 江苏省食品药品监督检验研究院 | 2023-04-18 | — | — | CN | claimed |
| WO-2023017035-A1 | HAIR COLORING COMPOSITIONS COMPRISING HYDROXYALKYL AMINES AS ALKALISING AGENTS | WELLA GERMANY GMBH (DE) | 2023-02-16 | — | — | WO | claimed |
| US-20230025989-A1 | COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR | L'OREAL (FR) | 2023-01-26 | — | — | US | claimed |
| WO-2023278726-A1 | COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR | L'OREAL (FR) | 2023-01-05 | — | — | WO | claimed |
| CN-114246807-A | Acidic hair dye composition | 朋友株式会社 | 2022-03-29 | — | — | CN | claimed |
| CN-112955112-A | Two-component system for artificial hair coloring | 汉高股份有限及两合公司 | 2021-06-11 | — | — | CN | claimed |
| US-9993413-B2 | Keratin fibre dyeing composition | BEAUTY & BUSINESS S.P.A. (IT) | 2018-06-12 | — | — | US | claimed |
| EP-1928397-A1 | METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS | E.I.Du pont de nemours and company (US) | 2008-06-11 | — | — | EP | claimed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | claimed |
| EP-1844816-A2 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'Oréal (FR) | 2007-10-17 | — | — | EP | claimed |
| WO-2007038733-A1 | METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-05 | — | — | WO | claimed |
| US-20070067924-A1 | Method for enhancing effects of colorants and conditioners | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-03-29 | — | — | US | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| US-4311478-A | HAIR DYES | L'OREAL (FR) | 1982-01-19 | — | — | US | claimed |
| US-4149848-A | N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES | L'OREAL (FR) | 1979-04-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025989-A1 | COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR | PHOSPHO1, TYR, AADAT | HCAR3 1205/4885ALDH1A1 1243/4885CRHBP 4121/4885 |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | HCAR3 2420/4885ALDH1A1 18/4885CRHBP 2768/4885 |
| US-20240350386-A1 | Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents | TYR, OGG1, UNG | HCAR3 585/4885ALDH1A1 6/4885CRHBP 4646/4885 |
| US-12036299-B2 | Compositions containing direct dyes for imparting color and tone to the hair | PHOSPHO1, TYR, AADAT | HCAR3 1205/4885ALDH1A1 1243/4885CRHBP 4121/4885 |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | HCAR3 3237/4885ALDH1A1 188/4885CRHBP 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.